DLST Back

dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

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NCBI Description of DLST
This gene encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene.

Community Annotation of DLST Add / Edit DLST: Annotations

No community annotations yet for DLST.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DLST is highly significantly mutated in
(none)
DLST is significantly mutated in
(none)
DLST is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DLST