discs, large (Drosophila) homolog-associated protein 2

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NCBI Description of DLGAP2

The product of this gene is a membrane-associated guanylate kinase. The encoded protein may play a role in synapse organization and signalling in neuronal cells. This gene is biallelically expressed in the brain, however, only the paternal allele is expressed in the testis (PMID:18055845). Alternatively spliced transcript variants encoding different isoforms have been identified.

Community Annotation of DLGAP2 Add / Edit DLGAP2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DLGAP2 is highly significantly mutated in
DLGAP2 is significantly mutated in
DLGAP2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DLGAP2