DLG2 Back

discs, large homolog 2, chapsyn-110 (Drosophila)

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NCBI Description of DLG2
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known.

Community Annotation of DLG2 Add / Edit DLG2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DLG2 is highly significantly mutated in
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DLG2 is significantly mutated in
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DLG2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DLG2