DLG1 Back

discs, large homolog 1 (Drosophila)

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NCBI Description of DLG1

This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene, but the full-length nature of some of the variants is not known.

Community Annotation of DLG1 Add / Edit DLG1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DLG1 is highly significantly mutated in
DLG1 is significantly mutated in
DLG1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DLG1