DLEC1 Back

deleted in lung and esophageal cancer 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DLEC1

This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney.

Community Annotation of DLEC1 Add / Edit DLEC1: Annotations

No community annotations yet for DLEC1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DLEC1 is highly significantly mutated in
DLEC1 is significantly mutated in
DLEC1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DLEC1