DLEC1 Back

deleted in lung and esophageal cancer 1

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NCBI Description of DLEC1
This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DLEC1 is highly significantly mutated in
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DLEC1 is significantly mutated in
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DLEC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DLEC1