DIS3L2 Back

DIS3 mitotic control homolog (S. cerevisiae)-like 2

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NCBI Description of DIS3L2
The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.

Community Annotation of DIS3L2 Add / Edit DIS3L2: Annotations

No community annotations yet for DIS3L2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DIS3L2 is highly significantly mutated in
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DIS3L2 is significantly mutated in
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DIS3L2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DIS3L2