DIRC2 Back

disrupted in renal carcinoma 2

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NCBI Description of DIRC2
This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence and transcripts to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Community Annotation of DIRC2 Add / Edit DIRC2: Annotations

No community annotations yet for DIRC2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DIRC2 is highly significantly mutated in
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DIRC2 is significantly mutated in
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DIRC2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DIRC2