DIP2B Back

DIP2 disco-interacting protein 2 homolog B (Drosophila)

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NCBI Description of DIP2B

This gene encodes a member of the disco-interacting protein homolog 2 protein family. The encoded protein contains a binding site for the transcriptional regulator DNA methyltransferase 1 associated protein 1 as well as AMP-binding sites. The presence of these sites suggests that the encoded protein may participate in DNA methylation. This gene is located near a folate-sensitive fragile site, and CGG-repeat expansion in the promoter of this gene which affects transcription has been detected in individuals containing this fragile site on chromosome 12.

Community Annotation of DIP2B Add / Edit DIP2B: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DIP2B is highly significantly mutated in
DIP2B is significantly mutated in
DIP2B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DIP2B