DHX37 Back

DEAH (Asp-Glu-Ala-His) box polypeptide 37

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NCBI Description of DHX37

This gene encodes a DEAD box protein. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.

Community Annotation of DHX37 Add / Edit DHX37: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DHX37 is highly significantly mutated in
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DHX37 is significantly mutated in
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DHX37 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for DHX37