DHX33 Back

DEAH (Asp-Glu-Ala-His) box polypeptide 33

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NCBI Description of DHX33
This gene encodes a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternative splicing results in multiple transcript variants.

Community Annotation of DHX33 Add / Edit DHX33: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DHX33 is highly significantly mutated in
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DHX33 is significantly mutated in
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DHX33 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DHX33