DHX16 Back

DEAH (Asp-Glu-Ala-His) box polypeptide 16

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DHX16
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of DHX16 Add / Edit DHX16: Annotations

No community annotations yet for DHX16.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DHX16 is highly significantly mutated in
(none)
DHX16 is significantly mutated in
(none)
DHX16 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DHX16