DGKZ Back

diacylglycerol kinase, zeta 104kDa

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NCBI Description of DGKZ

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified.

Community Annotation of DGKZ Add / Edit DGKZ: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DGKZ is highly significantly mutated in
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DGKZ is significantly mutated in
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DGKZ is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for DGKZ