DGKQ Back

diacylglycerol kinase, theta 110kDa

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NCBI Description of DGKQ
The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of DGKQ Add / Edit DGKQ: Annotations

No community annotations yet for DGKQ.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DGKQ is highly significantly mutated in
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DGKQ is significantly mutated in
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DGKQ is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DGKQ