DGKE Back

diacylglycerol kinase, epsilon 64kDa

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NCBI Description of DGKE
Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis.

Community Annotation of DGKE Add / Edit DGKE: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DGKE is highly significantly mutated in
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DGKE is significantly mutated in
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DGKE is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DGKE