DGCR6 Back

DiGeorge syndrome critical region gene 6

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NCBI Description of DGCR6
DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia.

Community Annotation of DGCR6 Add / Edit DGCR6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DGCR6 is highly significantly mutated in
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DGCR6 is significantly mutated in
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DGCR6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DGCR6