DGAT2 Back

diacylglycerol O-acyltransferase homolog 2 (mouse)

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NCBI Description of DGAT2

This gene encodes one of two enzymes which catalyzes the final reaction in the synthesis of triglycerides in which diacylglycerol is covalently bound to long chain fatty acyl-CoAs. The encoded protein catalyzes this reaction at low concentrations of magnesium chloride while the other enzyme has high activity at high concentrations of magnesium chloride. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of DGAT2 Add / Edit DGAT2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DGAT2 is highly significantly mutated in
DGAT2 is significantly mutated in
DGAT2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DGAT2