defensin, beta 4A

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NCBI Description of DEFB4A

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DEFB4A is highly significantly mutated in
DEFB4A is significantly mutated in
DEFB4A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DEFB4A