DEFB125 Back

defensin, beta 125

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DEFB125

Defensins are cysteine-rich cationic polypeptides that are important in the host immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.

Community Annotation of DEFB125 Add / Edit DEFB125: Annotations

No community annotations yet for DEFB125.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DEFB125 is highly significantly mutated in
DEFB125 is significantly mutated in
DEFB125 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DEFB125