NCBI Description of DEFB107A
|Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107A, represents the more centromeric copy.|
Community Annotation of DEFB107A Add / Edit DEFB107A: Annotations
No community annotations yet for DEFB107A.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.