DEFB104A Back

defensin, beta 104A

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DEFB104A

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy.

Community Annotation of DEFB104A Add / Edit DEFB104A: Annotations

No community annotations yet for DEFB104A.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DEFB104A is highly significantly mutated in
DEFB104A is significantly mutated in
DEFB104A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DEFB104A