DEFB103A Back

defensin, beta 103A

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NCBI Description of DEFB103A

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103B, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DEFB103A is highly significantly mutated in
DEFB103A is significantly mutated in
DEFB103A is near significance in

Click on a tumor type to see its full list of significant genes.