DDX6 Back

DEAD (Asp-Glu-Ala-Asp) box polypeptide 6

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NCBI Description of DDX6
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Community Annotation of DDX6 Add / Edit DDX6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DDX6 is highly significantly mutated in
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DDX6 is significantly mutated in
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DDX6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DDX6