DDX42 Back

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

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NCBI Description of DDX42
This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DDX42 is highly significantly mutated in
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DDX42 is significantly mutated in
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DDX42 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DDX42