DDX31 Back

DEAD (Asp-Glu-Ala-Asp) box polypeptide 31

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NCBI Description of DDX31

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants.

Community Annotation of DDX31 Add / Edit DDX31: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DDX31 is highly significantly mutated in
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DDX31 is significantly mutated in
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DDX31 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for DDX31