DDX20 Back

DEAD (Asp-Glu-Ala-Asp) box polypeptide 20

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DDX20
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.

Community Annotation of DDX20 Add / Edit DDX20: Annotations

No community annotations yet for DDX20.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DDX20 is highly significantly mutated in
(none)
DDX20 is significantly mutated in
(none)
DDX20 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DDX20