DDX10 Back

DEAD (Asp-Glu-Ala-Asp) box polypeptide 10

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DDX10
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies.

Community Annotation of DDX10 Add / Edit DDX10: Annotations

No community annotations yet for DDX10.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DDX10 is highly significantly mutated in
(none)
DDX10 is significantly mutated in
(none)
DDX10 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DDX10