DCTN6 Back

dynactin 6

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NCBI Description of DCTN6

The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known.

Community Annotation of DCTN6 Add / Edit DCTN6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DCTN6 is highly significantly mutated in
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DCTN6 is significantly mutated in
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DCTN6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for DCTN6