DCP2 Back

DCP2 decapping enzyme homolog (S. cerevisiae)

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NCBI Description of DCP2
The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Community Annotation of DCP2 Add / Edit DCP2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DCP2 is highly significantly mutated in
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DCP2 is significantly mutated in
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DCP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DCP2