DCN Back

decorin

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DCN
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.

Community Annotation of DCN Add / Edit DCN: Annotations

No community annotations yet for DCN.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DCN is highly significantly mutated in
(none)
DCN is significantly mutated in
(none)
DCN is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DCN