DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DCLRE1A

This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants.

Community Annotation of DCLRE1A Add / Edit DCLRE1A: Annotations

No community annotations yet for DCLRE1A.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DCLRE1A is highly significantly mutated in
DCLRE1A is significantly mutated in
DCLRE1A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DCLRE1A