DCLRE1A Back

DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae)

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NCBI Description of DCLRE1A
This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DCLRE1A is highly significantly mutated in
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DCLRE1A is significantly mutated in
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DCLRE1A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DCLRE1A