DCAF7 Back

DDB1 and CUL4 associated factor 7

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NCBI Description of DCAF7
This gene encodes a protein with multiple WD40 repeats which facilitate protein-protein interactions and thereby enable the assembly of multiprotein complexes. This protein has been shown to function as a scaffold protein for protein complexes involved in kinase signalling. This highly conserved gene is present in eukaryotic plants, fungi, and animals. The ortholog of this gene was first identified in plants as a key regulator of anthocyanin biosynthesis and flower pigmentation. Alternative splicing results in multiple transcript variants.

Community Annotation of DCAF7 Add / Edit DCAF7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DCAF7 is highly significantly mutated in
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DCAF7 is significantly mutated in
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DCAF7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DCAF7