DCAF12L1 Back

DDB1 and CUL4 associated factor 12-like 1

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NCBI Description of DCAF12L1

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

Community Annotation of DCAF12L1 Add / Edit DCAF12L1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DCAF12L1 is highly significantly mutated in
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DCAF12L1 is significantly mutated in
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DCAF12L1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for DCAF12L1