DCAF12 Back

DDB1 and CUL4 associated factor 12

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NCBI Description of DCAF12

This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates.

Community Annotation of DCAF12 Add / Edit DCAF12: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


DCAF12 is highly significantly mutated in
DCAF12 is significantly mutated in
DCAF12 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for DCAF12