DCAF11 Back

DDB1 and CUL4 associated factor 11

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NCBI Description of DCAF11
This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene.

Community Annotation of DCAF11 Add / Edit DCAF11: Annotations

No community annotations yet for DCAF11.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DCAF11 is highly significantly mutated in
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DCAF11 is significantly mutated in
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DCAF11 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DCAF11