DBN1 Back

drebrin 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of DBN1
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.

Community Annotation of DBN1 Add / Edit DBN1: Annotations

No community annotations yet for DBN1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DBN1 is highly significantly mutated in
(none)
DBN1 is significantly mutated in
(none)
DBN1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DBN1