DAPK2 Back

death-associated protein kinase 2

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NCBI Description of DAPK2
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

DAPK2 is highly significantly mutated in
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DAPK2 is significantly mutated in
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DAPK2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for DAPK2