cytohesin 1 interacting protein

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NCBI Description of CYTIP

The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.

Community Annotation of CYTIP Add / Edit CYTIP: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CYTIP is highly significantly mutated in
CYTIP is significantly mutated in
CYTIP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CYTIP