CYSLTR2 Back

cysteinyl leukotriene receptor 2

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NCBI Description of CYSLTR2
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CYSLTR2 is highly significantly mutated in
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CYSLTR2 is significantly mutated in
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CYSLTR2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CYSLTR2