CYR61 Back

cysteine-rich, angiogenic inducer, 61

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NCBI Description of CYR61

The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CYR61 is highly significantly mutated in
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CYR61 is significantly mutated in
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CYR61 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CYR61