CYP2J2 Back

cytochrome P450, family 2, subfamily J, polypeptide 2

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NCBI Description of CYP2J2
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CYP2J2 is highly significantly mutated in
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CYP2J2 is significantly mutated in
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CYP2J2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CYP2J2