CYP2A7 Back

cytochrome P450, family 2, subfamily A, polypeptide 7

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of CYP2A7
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Community Annotation of CYP2A7 Add / Edit CYP2A7: Annotations

No community annotations yet for CYP2A7.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CYP2A7 is highly significantly mutated in
(none)
CYP2A7 is significantly mutated in
(none)
CYP2A7 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CYP2A7