CYP26C1 Back

cytochrome P450, family 26, subfamily C, polypeptide 1

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NCBI Description of CYP26C1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues. This gene is adjacent to a related gene on chromosome 10q23.33.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CYP26C1 is highly significantly mutated in
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CYP26C1 is significantly mutated in
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CYP26C1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CYP26C1