CYP20A1 Back

cytochrome P450, family 20, subfamily A, polypeptide 1

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NCBI Description of CYP20A1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

Community Annotation of CYP20A1 Add / Edit CYP20A1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CYP20A1 is highly significantly mutated in
CYP20A1 is significantly mutated in
CYP20A1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CYP20A1