CYLC2 Back

cylicin, basic protein of sperm head cytoskeleton 2

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NCBI Description of CYLC2

Cylicin II (CYCL2) is specifically expressed in testis and is part of the cytoskeletal calyx of mammalian sperm heads. Cylicin II may play a role in the morphogenesis of the sperm head. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: This CCDS ID is based on a transcript that is a candidate for nonsense-mediated decay (NMD); however, the protein is supported by experimental evidence (PMID 7737358, 12747772) and by protein homology.

Community Annotation of CYLC2 Add / Edit CYLC2: Annotations

No community annotations yet for CYLC2.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CYLC2 is highly significantly mutated in
CYLC2 is significantly mutated in
CYLC2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CYLC2