CYGB Back

cytoglobin

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NCBI Description of CYGB

This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.

Community Annotation of CYGB Add / Edit CYGB: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CYGB is highly significantly mutated in
(none)
CYGB is significantly mutated in
(none)
CYGB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CYGB