CXCL13 Back

chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)

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NCBI Description of CXCL13
B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CXCL13 is highly significantly mutated in
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CXCL13 is significantly mutated in
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CXCL13 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CXCL13