CXCL10 Back

chemokine (C-X-C motif) ligand 10

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NCBI Description of CXCL10

This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.

Community Annotation of CXCL10 Add / Edit CXCL10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CXCL10 is highly significantly mutated in
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CXCL10 is significantly mutated in
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CXCL10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CXCL10