CX3CR1 Back

chemokine (C-X3-C motif) receptor 1

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NCBI Description of CX3CR1

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

Community Annotation of CX3CR1 Add / Edit CX3CR1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


CX3CR1 is highly significantly mutated in
CX3CR1 is significantly mutated in
CX3CR1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for CX3CR1