CTSZ Back

cathepsin Z

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NCBI Description of CTSZ

The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.

Community Annotation of CTSZ Add / Edit CTSZ: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CTSZ is highly significantly mutated in
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CTSZ is significantly mutated in
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CTSZ is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for CTSZ