CTSW Back

cathepsin W

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NCBI Description of CTSW
The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2.

Community Annotation of CTSW Add / Edit CTSW: Annotations

No community annotations yet for CTSW.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

CTSW is highly significantly mutated in
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CTSW is significantly mutated in
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CTSW is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for CTSW